949 research outputs found

    Workshop Using Myth, Storytelling, and Ritual in the Human Services

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    The study of workshops using myth, storytelling and ritual shows how these workshops can be helpful to adolescents. This paper examines a training workshop of the Hero\u27s Journey for human service professionals who work with adolescents and a workshop for adolescents using myth, storytelling and ritual. An analysis and discussion of surveys done with participants is included in the text

    Uveitis in human immunodeficiency virus-infected individuals

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    Author version made available in accordance with the publisher's policy.Since the first description in 1982 of ocular involvement in individuals testing positive for human immunodeficiency virus (HIV), a large volume of work has described the spectrum of uveitis that may occur in the setting of HIV infection. In this review we describe the causes of uveitis of HIV-positive persons, considering both infectious and noninfectious entities.Support: Australian Research Council (FT130101648

    The Forensic Imagination: Interdisciplinary Approaches to Tracing Creativity in Writers’ Born-Digital Archives

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    In 2013, Matthew Kirschenbaum advocated for increased collaboration between digital archivists and digital humanities specialists to make the most out of born-digital archives. Since then, researchers and archivists have experimented with innovative interfaces for access to writer’s archives that emerge from individual research cultures and practices. Simultaneously, archives such as the British Archive for Contemporary Writing (BACW) at the University of East Anglia (UEA) are beginning to collect the work of authors who work in inventive digital ways. This article will therefore explore the following question: how might archivists, authors and researchers profitably collaborate to explore the nature of creativity in the born-digital archive, so that both digital preservation and digital scholarship take place? In doing so, the authors look to the complementary fields of genetic criticism and digital humanities to inform the development of archival tools as ‘hermeneutical instruments’. They will explore how such instruments might allow us to read horizontally across archival strata, building on an ‘esthetic of the possible’ to develop a ‘jouer avec les fonds’, supported through collaboration between researchers, archivists and writers. Finally, the authors consider how this approach challenges archival practices, and propose forms of collaboration that might address both archival practice and emerging forms of scholarship

    Reviewing the Impact of the National Strategies Design and Technology Framework for Key Stage Three: A small-­‐scale evaluation of the Design and Technology Framework in England

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    Since the beginning of Design and Technology (D&T) in the English secondary school curriculum, the teaching of design has been identified as less effective than that of making. Research Questions: What are the experiences of pupils between the ages of 12 and 14 of design learning? Purpose of Study: In 2004 as part of the National Strategies, the D&T framework was launched, aiming to support the teaching of design skills. This is a small-­‐scale study, which begins to explore the experiences of pupils and teachers in four schools in the Northwest of England. Research Methods: The study used a mixed methods approach, gathering quantitative and qualitative data in a questionnaire with a convenience sample of school pupils. The questionnaire responses are analysed alongside qualitative interviews with D&T teachers from the schools. Findings: The findings indicate that many pupils had a clear understanding of the role of designing. However, some common assumptions of the nature of design activity centering on the act of sketching or drawing were evident. The majority of pupils were unable to accurately identify the names of many of the design activities introduced as part of the framework. Conclusions: Whilst some progress has been made in the teaching of design, through the use of design activities introduced in the D&T Framework, the support experienced by teachers was limited and were not sustained beyond the initial training. There are implications for initial teacher educators in supporting beginning teachers and balancing the tensions trainees experience whilst on placements in school. Key Words: Design, designing, pedagogy, teacher educatio

    Involvement of B cells in non-infectious uveitis

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    This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/Non-infectious uveitis—or intraocular inflammatory disease—causes substantial visual morbidity and reduced quality of life amongst affected individuals. To date, research of pathogenic mechanisms has largely been focused on processes involving T lymphocyte and/or myeloid leukocyte populations. Involvement of B lymphocytes has received relatively little attention. In contrast, B-cell pathobiology is a major field within general immunological research, and large clinical trials have showed that treatments targeting B cells are highly effective for multiple systemic inflammatory diseases. B cells, including the terminally differentiated plasma cell that produces antibody, are found in the human eye in different forms of non-infectious uveitis; in some cases, these cells outnumber other leukocyte subsets. Recent case reports and small case series suggest that B-cell blockade may be therapeutic for patients with non-infectious uveitis. As well as secretion of antibody, B cells may promote intraocular inflammation by presentation of antigen to T cells, production of multiple inflammatory cytokines and support of T-cell survival. B cells may also perform various immunomodulatory activities within the eye. This translational review summarizes the evidence for B-cell involvement in non-infectious uveitis, and considers the potential contributions of B cells to the development and control of the disease. Manipulations of B cells and/or their products are promising new approaches to the treatment of non-infectious uveitis
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